The video.

BRODYQUEST video This semi-meme refers to the popular, in which actor Adrian Brody is shown playing a guitar in outer space. Several ponychan members were talking about the video in chat, and the words "space" and "brilliant" were misspelled at some point. Laughs were had, and a couple macros were made. Mostly an injoke between participants, but it does persist now and then in threads.

It is one of the least relavant meme to the pony fandom. The video also won an Oscars acadamey award (see the second video below).